Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630979 | 0.84 | ALDH1A1 (0.96) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL1397690 | 0.84 | GAA (0.72) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL30290422 | 0.84 | GAA (0.72) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL1517128 | 0.84 | ALDH1A1 (0.96) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL3105857 | 0.84 | ALDH1A1 (0.96) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL8349198 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| Hydrochloric Acid SCHEMBL4630423 | 0.83 | GAA (0.70) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL27767932 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL1517203 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL29717077 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |