Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 9/20 | 0.43 |
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055964 | 0.86 | GRM5 (0.54) | GRM5ACHEHTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL30895650 | 0.85 | GRM5 (0.53) | GRM5ACHEHTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5250223 | 0.85 | GRM5 (0.53) | GRM5ACHEHTR2CHTR2BHTR2A | |
| SCHEMBL5249904 | 0.77 | GRM5 (0.54) | GRM5ACHEHTR2CHTR2BHTR2A | |
| SCHEMBL27304933 | 0.75 | ACHE (0.46) | GRM5ACHEHTR2ANPC1ALDH1A1 | |
| SCHEMBL31498948 | 0.74 | NPC1 (0.50) | ACHENPC1ALDH1A1RAB9ADRD3 | |
| SCHEMBL29438739 | 0.74 | HTT (0.51) | GRM5ACHENPC1ALDH1A1RAB9A | |
| SCHEMBL179076 | 0.74 | HTT (0.51) | GRM5ACHENPC1ALDH1A1RAB9A | |
| SCHEMBL1413616 | 0.73 | CYP1A2 (0.49) | ACHEHTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL7683501 | 0.72 | DRD3 (0.56) | ACHENPC1ALDH1A1RAB9ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006956-A9 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-11 | — | — | WO | disclosed |