Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537791 | 1.00 | CETP (0.54) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL17381379 | 1.00 | CETP (0.54) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL28554083 | 0.98 | ALDH1A1 (0.54) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL28556815 | 0.94 | ALDH1A1 (0.52) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL19105272 | 0.94 | ALDH1A1 (0.55) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL28670479 | 0.93 | MAPK1 (0.56) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL7641679 | 0.93 | CETP (0.50) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL7634006 | 0.93 | CETP (0.50) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL7637052 | 0.93 | CETP (0.50) | CETPALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL7640349 | 0.91 | ALDH1A1 (0.51) | CETPALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054599-C | Hydroxamic acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-07-19 | — | — | CN | disclosed |
| CN-1082027-A | Hydroxamic acid derivs | HOFFMANN LA ROCHE (CH) | 1994-02-16 | — | — | CN | disclosed |