Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.33 |
| ▸ | SCN2B | O60939 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL27451741 | 0.92 | OPRL1 (0.33) | PDE10AOPRL1SCN2BSCN1ASCN1B | |
| Acetaldehyde SCHEMBL7997949 | 0.92 | SCN2B (0.32) | PDE10AOPRL1SCN2BSCN1ASCN1B | |
| Acetonitrile SCHEMBL27369932 | 0.92 | LRRK2 (0.32) | PDE10AOPRL1 | |
| SCHEMBL6486723 | 0.84 | SCN2B (0.33) | OPRL1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL25928306 | 0.74 | HDAC4 (0.33) | HDAC4CYP11B2 | |
| SCHEMBL27610939 | 0.72 | — | — | |
| SCHEMBL13153481 | 0.71 | DAO (0.33) | — | |
| SCHEMBL28122066 | 0.71 | DAO (0.33) | — | |
| SCHEMBL6171362 | 0.71 | CHRNB2 (0.33) | — | |
| SCHEMBL6167739 | 0.70 | HTR2C (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053188-C | Quinolizinone type compounds | ABBOTT LAB (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1137273-A | Quinolizinone type compounds | ABBOTT LAB (US) | 1996-12-04 | — | — | CN | disclosed |