Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | DCAF1 | Q9Y4B6 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369968 | 0.81 | MAPK1 (0.35) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL27369938 | 0.79 | MAPK1 (0.42) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL35212433 | 0.75 | MAPK1 (0.39) | MAPK1DCAF1 | |
| SCHEMBL30937332 | 0.74 | MAPK1 (0.40) | MAPK1DCAF1 | |
| SCHEMBL27369957 | 0.74 | MAPK1 (0.39) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL27369904 | 0.73 | DCAF1 (0.51) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL27369980 | 0.72 | MAPK1 (0.38) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL27369930 | 0.72 | MAPK1 (0.38) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL27369965 | 0.72 | MAPK1 (0.38) | MAPK1AURKACDK2DCAF1 | |
| SCHEMBL35212404 | 0.71 | MAPK1 (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |