Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 15/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369957 | 0.89 | MAPK1 (0.39) | DCAF1MAPK1AURKACDK2CTSA | |
| SCHEMBL27369934 | 0.89 | DCAF1 (0.48) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL35212462 | 0.81 | DCAF1 (0.43) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL35212428 | 0.81 | DCAF1 (0.43) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL35212183 | 0.81 | DCAF1 (0.43) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL30937313 | 0.80 | DCAF1 (0.42) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL35212406 | 0.80 | DCAF1 (0.42) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL35211902 | 0.79 | DCAF1 (0.41) | DCAF1MAPK1AURKACDK2CNR2 | |
| SCHEMBL27369861 | 0.79 | DCAF1 (0.65) | DCAF1MAPK1CTSA | |
| SCHEMBL35211915 | 0.79 | DCAF1 (0.41) | DCAF1MAPK1AURKACDK2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |