Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.38 |
| ▸ | WIZ | O95785 | 1/20 | 0.32 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.32 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158065 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL29482803 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL21947846 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL29482859 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL29482849 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL24319777 | 0.78 | CRBN (0.62) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL26219172 | 0.78 | CRBN (0.53) | CRBN | |
| SCHEMBL30680831 | 0.71 | CRBN (0.59) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL24834119 | 0.71 | CRBN (0.59) | CRBNWIZIKZF2IKZF1CSNK1A1 | |
| SCHEMBL26969648 | 0.71 | CRBN (0.59) | CRBNWIZIKZF2IKZF1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |