Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772132 | 0.94 | ACE2 (0.36) | ACE2BLMCYP4F2CYP4A11 | |
| SCHEMBL31157063 | 0.79 | BLM (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL31157064 | 0.79 | BLM (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL30959045 | 0.79 | BLM (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL31157055 | 0.79 | BLM (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL31157050 | 0.79 | BLM (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL17772121 | 0.78 | CYP4F2 (0.41) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL17772130 | 0.78 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL2737164 | 0.77 | ACACB (0.51) | ACE2BLMCYP4F2CYP4A11TBXAS1 | |
| SCHEMBL798204 | 0.74 | TBXAS1 (0.45) | CYP4F2CYP4A11TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402300-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-04 | — | — | EP | disclosed |