Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690513 | 1.00 | TSHR (0.45) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3820431 | 0.84 | CA1 (0.45) | TSHRALDH1A1KDM4EKCNH2CA12 | |
| SCHEMBL29428931 | 0.84 | CA1 (0.45) | TSHRALDH1A1KDM4EKCNH2CA12 | |
| SCHEMBL7192709 | 0.83 | TSHR (0.43) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28962643 | 0.82 | TSHR (0.46) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL17365316 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8023262 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21497369 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL147382 | 0.81 | MAPT (0.47) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL31447203 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670108-A | Ether compounds as volatiles for treating amino acid based substrates such as skin and hair | 迈图高新材料有限责任公司 | 2023-08-29 | — | — | CN | claimed |
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | MABPLEX INTERNATIONAL, LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-11547697-B2 | Heterocyclic compounds and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-10752626-B2 | Iso-citrate dehydrogenase (IDH) inhibitor | SHANGHAI METON PHARMACEUTICAL CO., LTD (CN) | 2020-08-25 | — | — | US | disclosed |
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| US-20190350906-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2019-11-21 | — | — | US | disclosed |
| US-20190256511-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2019-08-22 | — | — | US | disclosed |
| US-20180153872-A1 | HETEROARYL CARBONITRILES FOR THE TREATMENT OF DISEASE | OPKO HEALTH, INC. | 2018-06-07 | — | — | US | disclosed |
| US-7226950-B2 | Sodium channel modulators | THERAVANCE, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| WO-2007059359-A2 | SUBSTITUTED PYRAZALONES | BIOGEN IDEC MA INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| CN-1886411-A | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEM IND CO (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-1313560-A4 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | UNIV YALE (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1313560-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6562989-B2 | Bicyclopentyl iron ligand and transition metal catalyst | YALE UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| US-20030008768-A1 | Catalyst for aromatic C-O, C-N, and C-C bond formation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| WO-2002011883-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2002-02-14 | — | — | WO | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| US-4654167-A | p-Alkoxycyclohexylalkanols and p-alkoxycyclohexylalkyl esters and their use as scents | BASF AKTIENGESELLSCHAFT (DE) | 1987-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | PIK3CA, PIK3CD, PIK3CB | TSHR 4257/4885MEN1 1016/4885NPC1 1284/4885 |
| US-20190256511-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | IDH3A, IDH2, IDH1 | TSHR 4426/4885MEN1 2874/4885NPC1 2029/4885 |
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | VIP, DNPEP, PREP | TSHR 2986/4885MEN1 1182/4885NPC1 2906/4885 |
| US-11547697-B2 | Heterocyclic compounds and uses thereof | PIK3CA, PIK3CD, PIK3CB | TSHR 4257/4885MEN1 1016/4885NPC1 1284/4885 |
| US-10752626-B2 | Iso-citrate dehydrogenase (IDH) inhibitor | IDH3A, IDH2, IDH1 | TSHR 4426/4885MEN1 2874/4885NPC1 2029/4885 |
| US-20180153872-A1 | HETEROARYL CARBONITRILES FOR THE TREATMENT OF DISEASE | CLN6, VHL, NPC1 | TSHR 2509/4885MEN1 824/4885NPC1 3/4885 |
| US-20190350906-A1 | Heterocyclic Compounds and Uses Thereof | PIK3CA, PIK3CD, PIK3CB | TSHR 4257/4885MEN1 1016/4885NPC1 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.