Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737156 | 0.98 | FFAR4 (0.41) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL12138679 | 0.94 | FFAR4 (0.39) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL1146781 | 0.92 | FFAR4 (0.42) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL1146226 | 0.90 | FFAR4 (0.39) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL14704335 | 0.86 | FFAR4 (0.39) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL1146831 | 0.85 | CYP1A2 (0.38) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL15417560 | 0.84 | FFAR4 (0.37) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL5903005 | 0.84 | PTPN1 (0.38) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL14150077 | 0.84 | ACACB (0.47) | FFAR4FFAR1GPR84FAAHACACB | |
| SCHEMBL1146690 | 0.84 | FFAR4 (0.37) | FFAR4FFAR1GPR84FAAHACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402300-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| US-8067466-B2 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management | ESPERION THERAPEUTICS, INC. (US) | 2011-11-29 | — | — | US | disclosed |