Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14704335 | 0.98 | FFAR4 (0.39) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL14150018 | 0.95 | FFAR4 (0.34) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL1146226 | 0.90 | FFAR4 (0.39) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL1146781 | 0.89 | FFAR4 (0.42) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL2737156 | 0.86 | FFAR4 (0.41) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL1146831 | 0.85 | CYP1A2 (0.38) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL2737155 | 0.84 | FFAR4 (0.44) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL10255305 | 0.84 | L3MBTL1 (0.34) | — | |
| SCHEMBL5902922 | 0.83 | PTPN1 (0.36) | FFAR4FFAR1GPR84ACACBACACA | |
| SCHEMBL1146783 | 0.82 | FFAR4 (0.35) | FFAR4FFAR1GPR84ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623915-B2 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. (US) | 2014-01-07 | — | — | US | disclosed |