SCHEMBL2737183

SCHEMBL2737183

Cc1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccc(S(=O)(=O)O)cc4)c4nc(c(-c5ccc(S(=O)(=O)O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.84

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 1/20 0.84
▸ TERT O14746 5/20 0.64
▸ TOP1 P11387 4/20 0.54
▸ CYCS P99999 3/20 0.52
▸ ABCG2 Q9UNQ0 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15943766 0.95 ENPP2 (0.76) ENPP2TERTTOP1CYCSABCG2
Hydrochloric Acid SCHEMBL29881399 0.93 ENPP2 (0.91) ENPP2TERTTOP1CYCSABCG2
SCHEMBL29368142 0.93 ENPP2 (0.97) ENPP2TERTTOP1CYCSABCG2
SCHEMBL218702 0.93 ENPP2 (0.97) ENPP2TERTTOP1CYCSABCG2
SCHEMBL2374278 0.92 ENPP2 (0.70) ENPP2TERTTOP1CYCSABCG2
Water SCHEMBL23522817 0.91 ENPP2 (0.94) ENPP2TERTTOP1CYCSABCG2
Ammonia Solution, Strong SCHEMBL3001889 0.91 ENPP2 (0.94) ENPP2TERTTOP1CYCSABCG2
SCHEMBL6139703 0.91 ENPP2 (0.94) ENPP2TERTTOP1CYCSABCG2
SCHEMBL17768419 0.91 ENPP2 (0.94) ENPP2TERTTOP1CYCSABCG2
Water SCHEMBL9870167 0.91 ENPP2 (0.94) ENPP2TERTTOP1CYCSABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839378-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2017-12-12 — — US disclosed
US-9757057-B2 Dry insertion and one-point in vivo calibration of an optical analyte sensor MEDTRONIC MINIMED, INC. (US) 2017-09-12 — — US disclosed
US-20170235034-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2017-08-17 — — US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 — — US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 — — US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 — — US disclosed
US-8979790-B2 Use of an equilibrium sensor to monitor glucose concentration MEDTRONIC MINIMED, INC. (US) 2015-03-17 — — US disclosed
US-20140350364-A1 OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION CITIBANK, N.A. 2014-11-27 — — US disclosed
US-8871926-B1 Synthesis of porphyrin nanostructures SANDIA CORPORATION (US) 2014-10-28 — — US disclosed
US-20140128694-A1 DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR GLUMETRICS, INC. (US) 2014-05-08 — — US disclosed
US-20140058225-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE GLUMETRICS, INC. (US) 2014-02-27 — — US disclosed
US-20140018646-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2014-01-16 — — US disclosed
US-20130287631-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION MEDTRONIC MINIMED, INC. 2013-10-31 — — US disclosed
US-8535262-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2013-09-17 — — US disclosed
US-8473222-B2 Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction GLUMETRICS, INC. (US) 2013-06-25 — — US disclosed
US-20120116191-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2012-05-10 — — US disclosed
US-8088097-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2012-01-03 — — US disclosed
US-20110224516-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION GLUMETRICS, INC. (US) 2011-09-15 — — US disclosed
US-20090177143-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL CITIBANK, N.A. 2009-07-09 — — US disclosed
Send feedback