Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520800 | 0.88 | LMNA (0.52) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL27371073 | 0.87 | LMNA (0.61) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL27428418 | 0.85 | LMNA (0.42) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL8851730 | 0.80 | LMNA (0.57) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL8851452 | 0.79 | TSHR (0.61) | LMNAEPHX2ALDH1A1CYP2C19MEN1 | |
| SCHEMBL22598135 | 0.79 | LMNA (0.52) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL11981936 | 0.79 | LMNA (0.40) | LMNAMAPTALDH1A1CYP2C19MEN1 | |
| SCHEMBL8104259 | 0.79 | LMNA (0.78) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL15391 | 0.79 | LMNA (0.78) | LMNAMAPTMAPK1EPHX2ALDH1A1 | |
| SCHEMBL18619 | 0.79 | LMNA (0.71) | LMNAMAPTMAPK1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053472-C | Oligonucleotides derived from the SOD family | HOFFMANN LA ROCHE (CH) | 2000-06-14 | — | — | CN | disclosed |
| CN-1106405-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | CN | disclosed |