Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | MC1R | Q01726 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374532 | 0.89 | HTR2A (0.50) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL28242499 | 0.79 | HTR2A (0.64) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL9559245 | 0.78 | MEN1 (0.68) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL6273998 | 0.77 | MEN1 (0.59) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL27174179 | 0.76 | HTR2A (0.66) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL678380 | 0.76 | HTR2A (0.69) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL28875080 | 0.76 | MEN1 (0.60) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| Hydrochloric Acid SCHEMBL5833228 | 0.74 | HTR2A (0.67) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL1972829 | 0.71 | HTR2A (1.00) | HTR2AKDM4EALDH1A1HTR1AHTT | |
| SCHEMBL761155 | 0.71 | MTNR1A (0.76) | MEN1KMT2ALMNACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006402-A1 | SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) DEGRADERS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-04 | — | — | WO | disclosed |