Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CALCA | P06881 | 2/20 | 0.33 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751367 | 1.00 | DYRK1A (0.37) | DYRK1AWNT1METRIPK1MAPK1 | |
| SCHEMBL30751355 | 0.95 | MET (0.37) | DYRK1AWNT1METBTKCALCA | |
| SCHEMBL27375170 | 0.95 | MET (0.37) | DYRK1AWNT1METBTKCALCA | |
| SCHEMBL27375683 | 0.94 | MET (0.38) | DYRK1AWNT1METBTKADORA1 | |
| SCHEMBL30751321 | 0.94 | MET (0.38) | DYRK1AWNT1METBTKADORA1 | |
| SCHEMBL27376866 | 0.94 | MET (0.37) | DYRK1AWNT1METBTK | |
| SCHEMBL30751461 | 0.94 | BTK (0.36) | DYRK1AWNT1METMAPK1BTK | |
| SCHEMBL27375904 | 0.94 | BTK (0.36) | DYRK1AWNT1METMAPK1BTK | |
| SCHEMBL30751315 | 0.93 | MET (0.36) | DYRK1AWNT1METMAPK1BTK | |
| SCHEMBL27374775 | 0.93 | MET (0.36) | DYRK1AWNT1METMAPK1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |