SCHEMBL27375147

SCHEMBL27375147

O=C1c2cc3cc4ccccc4cc3cc2C=CC1O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.32
GSTP1 P09211 1/20 0.31
CYP2D6 P10635 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9057236 0.97 NQO1 (0.33) NQO1GSTP1CYP2D6NPC1RAB9A
SCHEMBL29486506 0.78
SCHEMBL30753234 0.78
SCHEMBL1160393 0.76 NQO1 (0.31) NQO1
SCHEMBL10782968 0.76 GSTP1 (0.32) NQO1GSTP1NPC1RAB9A
SCHEMBL3309437 0.76 GRIN2D (0.34) NQO1GSTP1NPC1RAB9A
Hydrochloric Acid SCHEMBL7589943 0.75 NQO1 (0.33) NQO1
SCHEMBL8523526 0.74 CYP2D6 (0.42) CYP2D6
SCHEMBL7742245 0.73 CES1 (0.37) NQO1
SCHEMBL7742202 0.73 ALDH1A1 (0.35) NQO1GSTP1CYP2D6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1072172-A Novel 7-replacement-9-substituted-amino-6-demethyl-6-deoxidation tsiklomitsin AMERICAN CYANAMID CO (US) 1993-05-19 CN disclosed