Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456962 | 1.00 | TAAR1 (0.59) | TAAR1PRMT6ERN1KAT6AGRM5 | |
| SCHEMBL18876483 | 0.82 | ERN1 (0.49) | TAAR1PRMT6ERN1KAT6AGRM5 | |
| SCHEMBL109478 | 0.77 | TAAR1 (0.70) | TAAR1PRMT6ALDH1A1POLBHTR2C | |
| SCHEMBL28217068 | 0.77 | TAAR1 (0.58) | TAAR1PRMT6MEN1NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1014846 | 0.76 | TAAR1 (0.68) | TAAR1PRMT6ALDH1A1POLBHTR2C | |
| SCHEMBL112138 | 0.74 | TAAR1 (1.00) | TAAR1PRMT6HTR2C | |
| SCHEMBL24459423 | 0.73 | TAAR1 (0.58) | TAAR1 | |
| SCHEMBL18311308 | 0.71 | KAT6A (0.55) | TAAR1ERN1KAT6APTPN1 | |
| SCHEMBL19662062 | 0.71 | TAAR1 (0.58) | TAAR1PRMT6ERN1PIK3R1PIK3CA | |
| SCHEMBL30557741 | 0.71 | PIK3R1 (0.54) | TAAR1PRMT6ERN1PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |