Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109478 | 0.85 | TAAR1 (0.70) | TAAR1PRMT6KEAP1NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL1014846 | 0.83 | TAAR1 (0.68) | TAAR1PRMT6KEAP1NOS3NOS1 | |
| SCHEMBL27569385 | 0.80 | PRMT6 (0.49) | TAAR1PRMT6KEAP1SMARCA2PBRM1 | |
| SCHEMBL27375459 | 0.77 | TAAR1 (0.59) | TAAR1PRMT6HTR2CPOLBALDH1A1 | |
| SCHEMBL31456962 | 0.77 | TAAR1 (0.59) | TAAR1PRMT6HTR2CPOLBALDH1A1 | |
| SCHEMBL112138 | 0.73 | TAAR1 (1.00) | TAAR1PRMT6KEAP1CYP2A6HTR2C | |
| SCHEMBL4846415 | 0.72 | TAAR1 (0.54) | TAAR1PRMT6KEAP1SMARCA2PBRM1 | |
| SCHEMBL10177755 | 0.72 | TAAR1 (0.48) | TAAR1CYP2E1CYP3A4CYP2D6CYP2A6 | |
| SCHEMBL27559481 | 0.72 | PRMT6 (0.42) | TAAR1PRMT6KEAP1CYP3A4CYP2C9 | |
| SCHEMBL9454526 | 0.69 | PRMT6 (0.63) | TAAR1PRMT6KEAP1PSMB5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |