Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476477 | 0.88 | CYP1A2 (0.50) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL5582531 | 0.84 | NPC1 (0.50) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL1065921 | 0.75 | NPC1 (0.51) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL171746 | 0.74 | CYP1A2 (0.47) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL16215381 | 0.74 | BAZ2B (0.56) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL1673429 | 0.74 | BAZ2B (0.69) | NPC1RAB9ABAZ2BMAPTHTT | |
| SCHEMBL2245582 | 0.74 | BAZ2B (0.64) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL7653660 | 0.73 | NPC1 (0.49) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL2244056 | 0.72 | BAZ2B (0.67) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL2245426 | 0.72 | CYP1A2 (0.69) | NPC1RAB9ABAZ2BCYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052224-C | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 2000-05-10 | — | — | CN | disclosed |