Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454771 | 0.75 | MCHR1 (0.49) | NPC1RAB9ABAZ2BHTR2CMCHR1 | |
| SCHEMBL30661164 | 0.74 | MEN1 (0.39) | MAOAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9798491 | 0.74 | MEN1 (0.39) | MAOAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5582526 | 0.74 | MCHR1 (0.49) | NPC1RAB9ABAZ2BHTR2CMCHR1 | |
| SCHEMBL5582516 | 0.74 | MCHR1 (0.48) | NPC1RAB9ABAZ2BHTR2CMCHR1 | |
| SCHEMBL16215381 | 0.73 | BAZ2B (0.56) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL27375522 | 0.73 | NPC1 (0.53) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL5582597 | 0.71 | MCHR1 (0.54) | NPC1RAB9AHTR2CKDM4EMAPT | |
| SCHEMBL5582531 | 0.71 | NPC1 (0.50) | NPC1RAB9ABAZ2BCYP1A2ADRA2A | |
| SCHEMBL5582789 | 0.69 | MCHR1 (0.56) | NPC1RAB9AHTR2CALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |