⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL14012524 | 0.89 | — | — | |
| Fluorobenzene SCHEMBL7024891 | 0.89 | — | — | |
| Fluorobenzene SCHEMBL12363 | 0.89 | — | — | |
| SCHEMBL22526495 | 0.89 | NFE2L2 (0.53) | — | |
| Fluorobenzene SCHEMBL15544432 | 0.89 | NFE2L2 (0.53) | — | |
| Fluorobenzene SCHEMBL1891568 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL8174371 | 0.85 | — | — | |
| Fluorobenzene SCHEMBL12469089 | 0.85 | — | — | |
| Fluorobenzene SCHEMBL21829121 | 0.85 | — | — | |
| Fluorobenzene SCHEMBL15754920 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898425-B | 4,5-glyoxalidine [1,2-a] quinoline derivative and application of 4,5- glyoxalidine [1,2-a] quinoline derivative | HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY (CN) | 2014-10-08 | — | — | CN | disclosed |
| CN-102579989-B | Flunarizine hydrochloride and preparation process thereof | SHANDONG KERNEL AND HALL PHARMACEUTICAL INDUSTRY CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-102898425-A | 4,5-glyoxalidine [1,2-a] quinoline derivative and application of 4,5- glyoxalidine [1,2-a] quinoline derivative | HAFLRU | 2013-01-30 | — | — | CN | disclosed |
| CN-102579989-A | Flunarizine hydrochloride and preparation process thereof | SHANDONG KERNEL AND HALL PHARMACEUTICAL INDUSTRY CO LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-102186847-A | novel 2-amido thiadiazole derivatives | ALMIRALL SA | 2011-09-14 | — | — | CN | disclosed |
| CN-101663299-A | Thia (dia) zoles as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2010-03-03 | — | — | CN | disclosed |
| CN-1319957-C | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | SHISEIDO CO LTD (JP) | 2007-06-06 | — | — | CN | disclosed |
| CN-1562988-A | Method for synthesizing Lomerizine Hydrochlortde | CHANGAO MEDICINES TECH CO LTD (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1549809-A | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | ������������ʽ���� | 2004-11-24 | — | — | CN | disclosed |
| CN-1129578-C | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA (JP) | 2003-12-03 | — | — | CN | disclosed |
| CN-1286683-A | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA (JP) | 2001-03-07 | — | — | CN | disclosed |
| CN-1062349-A | Be used as the croak pyridine class of the 3-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-07-01 | — | — | CN | disclosed |