Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | CALCA | P06881 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376268 | 1.00 | ERCC1 (0.32) | ERCC1ERCC4CALCA | |
| SCHEMBL21181039 | 0.90 | BTK (0.34) | CALCA | |
| SCHEMBL27376279 | 0.86 | CALCA (0.33) | ERCC1ERCC4CALCA | |
| SCHEMBL27376433 | 0.85 | BTK (0.33) | — | |
| SCHEMBL21181263 | 0.85 | MAPK1 (0.32) | — | |
| SCHEMBL24428078 | 0.84 | BTK (0.31) | — | |
| SCHEMBL27376450 | 0.84 | ERCC1 (0.33) | ERCC1ERCC4CALCA | |
| SCHEMBL27376428 | 0.84 | BTK (0.30) | — | |
| SCHEMBL21181078 | 0.83 | BTK (0.34) | CALCA | |
| SCHEMBL21181255 | 0.82 | BTK (0.33) | CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |