Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343545 | 0.84 | HSD17B10 (0.70) | HSD17B10TSHRCXCL8PKMAGBL2 | |
| SCHEMBL29431167 | 0.84 | HSD17B10 (0.70) | HSD17B10TSHRCXCL8PKMAGBL2 | |
| SCHEMBL27364715 | 0.81 | CAMK2A (0.51) | HSD17B10TSHRGAANPSR1AKR1B1 | |
| SCHEMBL23229170 | 0.80 | HSD17B10 (0.51) | HSD17B10TSHRCXCL8PKMAGBL2 | |
| SCHEMBL2445135 | 0.80 | HSD17B10 (0.51) | HSD17B10TSHRCXCL8PKMAGBL2 | |
| SCHEMBL27355584 | 0.79 | CHRM1 (0.54) | HSD17B10TSHRCXCL8CHRM1FFAR1 | |
| SCHEMBL27382354 | 0.79 | PTGDR2 (0.51) | HSD17B10TSHRPTGDR2SMN1; SMN2 | |
| SCHEMBL27363505 | 0.79 | SRC (0.50) | HSD17B10TSHRGAAPTGDR2PPARG | |
| SCHEMBL27357259 | 0.79 | PTGDR2 (0.46) | HSD17B10FFAR1FFAR4PTGDR2 | |
| SCHEMBL27354316 | 0.78 | CXCL8 (0.59) | CXCL8CHRM1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |