Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 7/20 | 0.39 |
| ▸ | AXL | P30530 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751111 | 1.00 | GRIN2B (0.41) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL31456948 | 1.00 | GRIN2B (0.41) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL31457001 | 0.96 | GRIN2B (0.43) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL30751096 | 0.96 | GRIN2B (0.43) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL30751314 | 0.93 | GRIN2B (0.36) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL30751271 | 0.89 | GRIN2B (0.38) | GRIN2BMETTRPC3TRPC7MERTK | |
| SCHEMBL31457054 | 0.89 | MET (0.40) | GRIN2BMETMERTKAXLTYRO3 | |
| SCHEMBL30751262 | 0.89 | MET (0.40) | GRIN2BMETMERTKAXLTYRO3 | |
| SCHEMBL30751331 | 0.89 | MET (0.40) | GRIN2BMETMERTKAXLTYRO3 | |
| SCHEMBL31457006 | 0.89 | MET (0.40) | GRIN2BMETMERTKAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |