Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.47 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.40 |
| ▸ | WNT1 | P04628 | 3/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 3/20 | 0.35 |
| ▸ | MERTK | Q12866 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751474 | 1.00 | MET (0.47) | METGSK3BDYRK1AWNT1EZH2 | |
| Hydrochloric Acid SCHEMBL30751296 | 0.99 | MET (0.47) | METGSK3BDYRK1AWNT1EZH2 | |
| SCHEMBL27376421 | 0.95 | MET (0.46) | METGSK3BDYRK1AWNT1EZH2 | |
| SCHEMBL21174281 | 0.95 | MET (0.50) | METKITMAPK1BTKPDPK1 | |
| Hydrochloric Acid SCHEMBL30751288 | 0.95 | MET (0.46) | METGSK3BDYRK1AWNT1EZH2 | |
| SCHEMBL21174231 | 0.94 | MET (0.49) | METDYRK1AEZH2KITMAPK1 | |
| SCHEMBL21174064 | 0.94 | MET (0.49) | METDYRK1AEZH2KITMAPK1 | |
| SCHEMBL30751108 | 0.92 | MET (0.47) | METGSK3BDYRK1AWNT1KIT | |
| SCHEMBL27376365 | 0.92 | MET (0.47) | METGSK3BDYRK1AWNT1KIT | |
| SCHEMBL21174178 | 0.92 | MET (0.47) | METGSK3BDYRK1AWNT1EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |