Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751076 | 1.00 | MET (0.35) | METMAPK1MAP4K4BTKGRIN2B | |
| SCHEMBL30751355 | 0.92 | MET (0.37) | METBTKDYRK1ATRPA1KIT | |
| SCHEMBL27375170 | 0.92 | MET (0.37) | METBTKDYRK1ATRPA1KIT | |
| SCHEMBL27376866 | 0.91 | MET (0.37) | METBTKDYRK1ATRPA1KIT | |
| SCHEMBL21174259 | 0.89 | MET (0.46) | METMAPK1BTKCHRM1KIT | |
| SCHEMBL30751074 | 0.89 | MET (0.36) | METMAPK1BTKDYRK1ATRPA1 | |
| SCHEMBL30751316 | 0.89 | MET (0.36) | METMAPK1BTKDYRK1ATRPA1 | |
| SCHEMBL30751057 | 0.89 | MET (0.36) | METDYRK1ATRPA1KITNR2E3 | |
| SCHEMBL27377149 | 0.89 | MET (0.36) | METMAPK1BTKDYRK1ATRPA1 | |
| SCHEMBL30751091 | 0.88 | MET (0.35) | METBTKDYRK1ATRPA1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |