Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751055 | 1.00 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL27377149 | 0.93 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL30751316 | 0.93 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL30751057 | 0.93 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL30751051 | 0.92 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL27376895 | 0.92 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL31457000 | 0.92 | MET (0.36) | METAPOL1KITNR2E3TRPA1 | |
| SCHEMBL30751355 | 0.91 | MET (0.37) | METKITNR2E3TRPA1DYRK1A | |
| SCHEMBL27375170 | 0.91 | MET (0.37) | METKITNR2E3TRPA1DYRK1A | |
| SCHEMBL30751091 | 0.91 | MET (0.35) | METKITNR2E3TRPA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |