Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 3/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377147 | 0.88 | CCNC (0.33) | SCN9ABRD4KCNH2BCHECNR2 | |
| SCHEMBL27378341 | 0.82 | SCN9A (0.38) | SCN9ABRD4BCHECNR2DDB1 | |
| SCHEMBL27377137 | 0.81 | ATR (0.46) | SCN9ABRD4KCNH2BCHECNR2 | |
| SCHEMBL30797758 | 0.81 | ATR (0.46) | SCN9ABRD4KCNH2BCHECNR2 | |
| SCHEMBL27376547 | 0.78 | SCN9A (0.37) | SCN9ABRD4BCHECNR2DDB1 | |
| SCHEMBL27377504 | 0.71 | CSNK2A2 (0.37) | SCN9ABRD4BCHECNR2DDB1 | |
| SCHEMBL27377011 | 0.70 | DDB1 (0.34) | SCN9ABRD4BCHECNR2DDB1 | |
| SCHEMBL27377165 | 0.70 | BRD4 (0.34) | SCN9ABRD4CA12CA1CA2 | |
| SCHEMBL30797714 | 0.70 | ATR (0.41) | SCN9ABRD4KCNH2TRIM24ATR | |
| SCHEMBL27377150 | 0.70 | ATR (0.41) | SCN9ABRD4KCNH2TRIM24ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |