Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | FPR3 | P25089 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797714 | 1.00 | ATR (0.41) | ATRPRMT5WDR77RXRARXRB | |
| SCHEMBL27377137 | 0.89 | ATR (0.46) | ATRPRMT5WDR77RXRARXRB | |
| SCHEMBL30797758 | 0.89 | ATR (0.46) | ATRPRMT5WDR77RXRARXRB | |
| SCHEMBL30797857 | 0.88 | ATR (0.41) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30869032 | 0.85 | ATR (0.42) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30869070 | 0.85 | ATR (0.42) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797547 | 0.85 | ATR (0.42) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797730 | 0.84 | ATR (0.44) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797974 | 0.84 | ATR (0.44) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797688 | 0.84 | ATR (0.44) | ATRRXRARXRBRXRGBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |