Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797974 | 0.88 | ATR (0.44) | ATRRXRARXRBRXRGKRAS | |
| SCHEMBL30797688 | 0.88 | ATR (0.44) | ATRRXRARXRBRXRGKRAS | |
| SCHEMBL27377428 | 0.87 | ATR (0.39) | ATRRXRARXRBRXRGKRAS | |
| SCHEMBL30797677 | 0.86 | ATR (0.41) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797873 | 0.86 | ATR (0.41) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL27377014 | 0.86 | ATR (0.41) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL27377168 | 0.86 | ATR (0.41) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797730 | 0.86 | ATR (0.44) | ATRRXRARXRBRXRGBRD4 | |
| SCHEMBL30797751 | 0.85 | BRD4 (0.46) | ATRRXRARXRBRXRGKRAS | |
| SCHEMBL30797857 | 0.85 | ATR (0.41) | ATRRXRARXRBRXRGKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584266-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |