Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 9/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797873 | 1.00 | ATR (0.41) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797746 | 0.89 | ATR (0.46) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL27378404 | 0.89 | ATR (0.46) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797688 | 0.89 | ATR (0.44) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797547 | 0.86 | ATR (0.42) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL27377014 | 0.86 | ATR (0.41) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797677 | 0.86 | ATR (0.41) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797974 | 0.86 | ATR (0.44) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL30797730 | 0.84 | ATR (0.44) | ATRBRD4RXRARXRBRXRG | |
| SCHEMBL27377165 | 0.84 | BRD4 (0.34) | BRD4ADORA2AADORA1CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |