Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761908 | 1.00 | CASP3 (0.66) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30761909 | 1.00 | CASP3 (0.66) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16635672 | 0.90 | CASP3 (0.58) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18669155 | 0.87 | KMT2A (0.75) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31752966 | 0.86 | KMT2A (0.63) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30296449 | 0.85 | CASP3 (0.88) | CASP3KDM4EMEN1KMT2ACMA1 | |
| SCHEMBL45154 | 0.85 | CASP3 (0.88) | CASP3KDM4EMEN1KMT2ACMA1 | |
| SCHEMBL17029125 | 0.82 | CASP3 (0.66) | CASP3MEN1KMT2AALDH1A1POLB | |
| SCHEMBL2297050 | 0.80 | CASP3 (0.57) | CASP3KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL4728227 | 0.80 | TDP1 (0.66) | CASP3KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057190-A2 | TARGETED COMPOSITIONS | GENEVANT SCIENCES GMBH (CH) | 2024-03-21 | — | — | WO | disclosed |