SCHEMBL27378469

COP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)OCC1OC(n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	11/20	0.67

▸	P2RY1	P47900	3/20	0.64

▸	P2RY2	P41231	2/20	0.64

▸	SRC	P12931	1/20	0.64

▸	P2RX1	P51575	1/20	0.64

▸	P2RX3	P56373	1/20	0.64

▸	P2RX4	Q99571	1/20	0.64

▸	P2RX2	Q9UBL9	1/20	0.64

▸	ALDH1A1	P00352	1/20	0.64

▸	SMN1; SMN2	Q16637	1/20	0.64

▸	TGM2	P21980	1/20	0.63

▸	NT5E	P21589	1/20	0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27376664	0.97	RNASEL (0.65)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL27376774	0.97	RNASEL (0.65)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL30084833	0.94	RNASEL (0.76)	RNASELP2RY1P2RY2SRCSMN1; SMN2
SCHEMBL9951563	0.94	RNASEL (0.76)	RNASELP2RY1P2RY2SRCSMN1; SMN2
SCHEMBL23776029	0.93	RNASEL (0.68)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL21127880	0.93	RNASEL (0.66)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL21127990	0.93	RNASEL (0.66)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL21127910	0.93	RNASEL (0.66)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL21127813	0.93	RNASEL (0.66)	RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL30256778	0.93	RNASEL (0.71)	RNASELP2RY1P2RY2SRCP2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024072904-A2	PURIFICATION OF NUCLEOTIDES	MODERNATX, INC. (US)	2024-04-04	—	—	WO	disclosed