Acetonitrile

Acetonitrile

SCHEMBL27378482

CC#N.O=[N+]([O-])c1ccc(Cl)cc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.50
VCAM1 P19320 2/20 0.50
ACHE P22303 1/20 0.50
MAOB P27338 2/20 0.46
MAOA P21397 1/20 0.46
IDO1 P14902 1/20 0.46
RECQL P46063 1/20 0.45
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 2/20 0.45
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
RAB9A P51151 1/20 0.45
MCL1 Q07820 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28322379 0.89 CYP1A2 (0.64) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
Acetonitrile SCHEMBL28782625 0.87 ALDH1A1 (0.58) ALDH1A1HSD17B10VCAM1ACHERECQL
SCHEMBL11320631 0.87 CYP1A2 (0.67) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL2724772 0.87 CYP1A2 (0.67) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL28180410 0.87 CYP1A2 (0.67) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL29242 0.87 CYP1A2 (0.67) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
Methyl Alcohol SCHEMBL27437903 0.85 CYP1A2 (0.60) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL28546705 0.84 CYP1A2 (0.64) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
Fluoride SCHEMBL8146479 0.84 CYP1A2 (0.64) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL28429390 0.84 CYP1A2 (0.64) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619334-A Thiazolidine derivatives and their therapeutic use ZHU HONGWEN 2014-03-05 CN disclosed
CN-1312246-A Process for preparing carboxylic acid BAYER AG (DE) 2001-09-12 CN disclosed
CN-1067393-C Novel pyrimido [1, 2-a ] indoles BAYER AG (DE) 2001-06-20 CN disclosed
CN-1176965-A Novel pyrimido [1, 2-a ] indoles BAYER AG (DE) 1998-03-25 CN disclosed