Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326549 | 0.90 | HSD17B10 (0.38) | ALDH1A1MEN1RAB9AKMT2AHSD17B10 | |
| SCHEMBL27378764 | 0.85 | TNKS2 (0.39) | ALDH1A1MEN1RAB9AKMT2AHSD17B10 | |
| SCHEMBL27381086 | 0.84 | ERCC5 (0.34) | ERCC5FEN1CHEK1ADRA1B | |
| SCHEMBL27192121 | 0.80 | MAPK14 (0.33) | ERCC5FEN1 | |
| SCHEMBL30701990 | 0.80 | MAPK14 (0.33) | ERCC5FEN1 | |
| SCHEMBL27378775 | 0.80 | ERCC5 (0.38) | ALDH1A1MEN1KMT2AERCC5FEN1 | |
| SCHEMBL27192043 | 0.79 | ERCC5 (0.36) | ALDH1A1MEN1KMT2AERCC5FEN1 | |
| SCHEMBL30702084 | 0.79 | ERCC5 (0.36) | ALDH1A1MEN1KMT2AERCC5FEN1 | |
| SCHEMBL27379530 | 0.77 | TNKS2 (0.35) | ALDH1A1MEN1KMT2AHSD17B10ERCC5 | |
| SCHEMBL27381102 | 0.75 | MAP4K1 (0.33) | HSD17B10ERCC5FEN1EGLN3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |