Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 7/20 | 0.34 |
| ▸ | JAK2 | O60674 | 6/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27378784 | 0.90 | ALDH1A1 (0.34) | HSD17B10ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL29326514 | 0.85 | TNKS2 (0.41) | HSD17B10ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL29326494 | 0.79 | ERCC5 (0.35) | HSD17B10ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL29326530 | 0.79 | ERCC5 (0.42) | ERCC5FEN1BTKJAK2MAPK14 | |
| SCHEMBL29326527 | 0.77 | HCAR1 (0.40) | HSD17B10ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL27378764 | 0.75 | TNKS2 (0.39) | HSD17B10ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL27381086 | 0.74 | ERCC5 (0.34) | ERCC5FEN1ADRA1BMAPK14 | |
| SCHEMBL29326555 | 0.73 | ERCC5 (0.36) | ALDH1A1ERCC5FEN1ADRA1BMAPK14 | |
| SCHEMBL29326162 | 0.72 | CYP1A1 (0.53) | ALDH1A1TDP1ERCC5FEN1BTK | |
| SCHEMBL29326453 | 0.72 | CYP1A1 (0.47) | HSD17B10ALDH1A1MEN1KMT2AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | HSD17B10 433/4885ALDH1A1 3259/4885TDP1 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.