Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.94 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | AGXT | P21549 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311581 | 0.97 | TSHR (1.00) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL27380 | 0.97 | TSHR (1.00) | TSHRIDO1AGXTCA1CA2 | |
| Water SCHEMBL15535487 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL9491202 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| Potassium SCHEMBL586337 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL574533 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| Ammonia Solution, Strong SCHEMBL8645051 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| Barium SCHEMBL3798966 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| Hydrochloric Acid SCHEMBL11878622 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| Water SCHEMBL10609439 | 0.94 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525880-B1 | Catalytic alkylation process | FMC CORP (US) | 1998-05-06 | — | — | EP | claimed |
| US-5332853-A | Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst | FMC CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
| EP-0525880-A1 | Catalytic alkylation process | FMC CORPORATION (US) | 1993-02-03 | — | — | EP | claimed |
| US-4051320-A | PROCESS FOR PREPARING ALKOXYLATED DERIVATIVES OF CEPHALOSPORIN COMPOUNDS | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | claimed |
| EP-3587490-B1 | METHACRYLIC RESIN COMPOSITION AND USE THEREOF | KURARAY CO (JP) | 2022-10-12 | — | — | EP | disclosed |
| US-11299600-B2 | Methacrylic resin composition and use thereof | KURARAY CO., LTD. (JP) | 2022-04-12 | — | — | US | disclosed |
| US-20210077420-A1 | Methods of Treatment of Gout | HOOPER MARK (GB) | 2021-03-18 | — | — | US | disclosed |
| US-20200377688-A1 | METHACRYLIC RESIN COMPOSITION AND USE THEREOF | KURARAY CO., LTD. (JP) | 2020-12-03 | — | — | US | disclosed |
| EP-3723741-A1 | DISSOLUTION OF MONOSODIUM URATE TO TREAT GOUT | Hooper, Mark (GB) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019116045-A1 | DISSOLUTION OF MONOSODIUM URATE TO TREAT GOUT | HOOPER MARK (GB) | 2019-06-20 | — | — | WO | disclosed |
| US-8119749-B2 | Method of taking (meth)acrylic ester polymer out of liquid reaction mixture | KURARAY CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| EP-1916262-B1 | METHOD OF TAKING (METH)ACRYLIC ESTER POLYMER OUT OF LIQUID REACTION MIXTURE | KURARAY CO (JP) | 2012-02-15 | — | — | EP | disclosed |
| EP-0279463-A2 | Graft polymerization of substituted styrene polymers having pendant vinylidene groups | Nippon Paint Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4525309-A | Lewis acid catalysis of the homologation of boronic esters with haloalkylmetal reagents | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1985-06-25 | — | — | US | disclosed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4051320-A | PROCESS FOR PREPARING ALKOXYLATED DERIVATIVES OF CEPHALOSPORIN COMPOUNDS | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | disclosed |
| US-4048160-A | Process for preparation of 7-alkoxy-3-bromomethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048163-A | Process for preparation of 7-alkoxy-3-chloromethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4044000-A | Substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3994885-A | WITH ALKALI METAL ALKOXIDE, HALOGENATION | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077420-A1 | Methods of Treatment of Gout | XDH, SLC10A1, LIPA | TSHR 3963/4885IDO1 4149/4885AGXT 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.