Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 16/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | ULK1 | O75385 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | CCNK | O75909 | 2/20 | 0.48 |
| ▸ | CCND3 | P30281 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27380915 | 0.86 | LRRK2 (0.55) | LRRK2JAK2ULK1CDK9 | |
| SCHEMBL27378090 | 0.81 | LRRK2 (0.62) | LRRK2JAK2ULK1 | |
| SCHEMBL7458726 | 0.78 | LRRK2 (1.00) | LRRK2JAK2CDK9 | |
| SCHEMBL27228532 | 0.76 | LRRK2 (0.58) | LRRK2JAK2 | |
| SCHEMBL30914274 | 0.76 | LRRK2 (0.58) | LRRK2JAK2 | |
| SCHEMBL21658531 | 0.75 | LRRK2 (0.75) | LRRK2JAK2CCNA2CDK2CCNK | |
| SCHEMBL14860727 | 0.74 | LRRK2 (0.67) | LRRK2JAK2CCNA2CDK2CCNK | |
| SCHEMBL15946660 | 0.74 | LRRK2 (0.64) | LRRK2JAK2 | |
| SCHEMBL28085028 | 0.74 | LRRK2 (1.00) | LRRK2JAK2ULK1 | |
| SCHEMBL27382028 | 0.73 | LRRK2 (0.46) | LRRK2JAK2ULK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |