Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384655 | 0.88 | EIF4A3 (0.48) | MAPK1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL27384854 | 0.88 | MAPK1 (0.41) | MAPK1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL27384340 | 0.87 | EIF4A3 (0.47) | MAPK1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL27384648 | 0.85 | EIF4A3 (0.48) | MAPK1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL27384336 | 0.83 | MAPK1 (0.40) | MAPK1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL27384264 | 0.83 | MAPK1 (0.40) | MAPK1RAB9ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL27382487 | 0.82 | HSD17B10 (0.46) | RAB9ASMN1; SMN2CYP1A2KDM4EMEN1 | |
| SCHEMBL27382492 | 0.80 | HSD17B10 (0.45) | MAPK1RAB9ASMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL27384644 | 0.80 | MAPK1 (0.46) | MAPK1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL27384649 | 0.79 | HTT (0.42) | MAPK1RAB9ASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |