Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382492 | 0.87 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A | |
| SCHEMBL27382678 | 0.85 | EIF4A3 (0.56) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A | |
| SCHEMBL27383362 | 0.83 | RAB9A (0.38) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A | |
| SCHEMBL27384339 | 0.82 | MAPK1 (0.42) | HSD17B10KDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL27382672 | 0.81 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A | |
| SCHEMBL27382677 | 0.78 | RAB9A (0.48) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A | |
| SCHEMBL27382556 | 0.74 | EIF4A3 (0.54) | KDM4ESMN1; SMN2RAB9ATSHRNPC1 | |
| SCHEMBL27384491 | 0.73 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BMAPTSMN1; SMN2RAB9A | |
| SCHEMBL27382673 | 0.73 | EIF4A3 (0.53) | HSD17B10KDM4EALDH1A1MTNR1AMTNR1B | |
| SCHEMBL27382489 | 0.71 | SMN1; SMN2 (0.47) | HSD17B10KDM4EALDH1A1CYP1A2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |