Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.33 |
| ▸ | METTL14 | Q9HCE5 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | APOL1 | O14791 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384348 | 0.92 | EIF4A3 (0.46) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27384648 | 0.87 | EIF4A3 (0.48) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27384655 | 0.87 | EIF4A3 (0.48) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27384340 | 0.86 | EIF4A3 (0.47) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27384346 | 0.83 | EIF4A3 (0.45) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27384342 | 0.81 | EIF4A3 (0.42) | EIF4A3RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL27382678 | 0.81 | EIF4A3 (0.56) | EIF4A3RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27383728 | 0.80 | RAB9A (0.53) | EIF4A3RAB9ANPC1SMN1; SMN2METTL3 | |
| SCHEMBL27382556 | 0.79 | EIF4A3 (0.54) | EIF4A3RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27382673 | 0.78 | EIF4A3 (0.53) | EIF4A3RAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |