Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.68 |
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960292 | 0.94 | MRGPRX4 (0.72) | MRGPRX4MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL10659025 | 0.89 | MRGPRX4 (0.74) | MRGPRX4MAOBMAOA | |
| SCHEMBL21578904 | 0.86 | MRGPRX4 (0.76) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL15296747 | 0.84 | MAOB (0.74) | MRGPRX4MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL3646136 | 0.84 | RAB9A (0.65) | MRGPRX4MAOBRAB9ASMN1; SMN2TP53 | |
| SCHEMBL12885852 | 0.84 | MRGPRX4 (0.74) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL23189125 | 0.84 | MAOB (0.82) | MRGPRX4MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL6959174 | 0.84 | NPC1 (0.73) | MAOBMAOARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2196098 | 0.83 | MAOB (0.75) | MRGPRX4MAOBMAOA | |
| SCHEMBL21221698 | 0.83 | MRGPRX4 (0.72) | MRGPRX4MAOBRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068308-C | Substituted benzoylguanide preparation and pharmaceutical application of same | HOECHST AG (DE) | 2001-07-11 | — | — | CN | disclosed |
| CN-1097737-A | Benzoyl guanidine, its method for making that replaces and contain their medicine and application | HOECHST AG (DE) | 1995-01-25 | — | — | CN | disclosed |