Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383027 | 1.00 | PIK3CA (0.52) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL27384001 | 1.00 | PIK3CA (0.52) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| Trifluoroacetic Acid SCHEMBL30857932 | 0.95 | PIK3CA (0.48) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30857904 | 0.88 | PIK3CA (0.46) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30857976 | 0.88 | PIK3CA (0.46) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30857944 | 0.88 | PIK3CA (0.46) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25219256 | 0.84 | PIK3CA (0.74) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30434657 | 0.84 | PIK3CA (0.74) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL24912818 | 0.77 | PIK3CA (0.72) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL24912829 | 0.77 | PIK3CA (0.72) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081904-A1 | METHODS FOR TREATING CANCER | GENESIS THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |