Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30857932

Cc1cc2c(=O)cc(-c3ccncc3)oc2c([C@@H](C)Nc2ccccc2C(=O)O)n1.O=C(O)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PIK3CA P42336 19/20 0.48
▸ PIK3CB P42338 2/20 0.48
▸ PIK3CD O00329 1/20 0.48
▸ PIK3CG P48736 1/20 0.48
▸ MTOR P42345 1/20 0.41
▸ PRKDC P78527 1/20 0.41
▸ PIK3C3 Q8NEB9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27385365 0.95 PIK3CA (0.52) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL27383027 0.95 PIK3CA (0.52) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL27384001 0.95 PIK3CA (0.52) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL30857904 0.85 PIK3CA (0.46) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL30857976 0.85 PIK3CA (0.46) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL30857944 0.85 PIK3CA (0.46) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL25219256 0.80 PIK3CA (0.74) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL30434657 0.80 PIK3CA (0.74) PIK3CAPIK3CBPIK3CDPIK3CGMTOR
SCHEMBL25531609 0.74 PIK3CA (0.73) PIK3CAPIK3CBMTORPRKDCPIK3C3
SCHEMBL24912982 0.74 PIK3CA (0.68) PIK3CAPIK3CBMTORPRKDCPIK3C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602031-A1 METHODS FOR TREATING CANCER Genesis Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
WO-2024081904-A1 METHODS FOR TREATING CANCER GENESIS THERAPEUTICS, INC. (US) 2024-04-18 — — WO disclosed
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