⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942620 | 0.81 | — | — | |
| SCHEMBL2738585 | 0.81 | — | — | |
| SCHEMBL14533807 | 0.81 | — | — | |
| SCHEMBL17400883 | 0.78 | — | — | |
| SCHEMBL17428634 | 0.75 | — | — | |
| SCHEMBL1472300 | 0.69 | — | — | |
| SCHEMBL20048887 | 0.69 | — | — | |
| SCHEMBL5904396 | 0.68 | — | — | |
| SCHEMBL10404 | 0.68 | — | — | |
| SCHEMBL12819706 | 0.67 | EPHX2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067344-B1 | CYCLOALKYL UREA DERIVATIVE | SUMITOMO PHARMA CO LTD (JP) | 2025-11-26 | — | — | EP | disclosed |
| CN-115003655-B | Cycloalkyl urea derivatives | 住友制药株式会社 | 2025-03-21 | — | — | CN | disclosed |
| US-20250066342-A1 | CYCLOALKYLUREA DERIVATIVE | Jazz Pharmaceuticals Therapeutics, Inc. | 2025-02-27 | — | — | US | disclosed |
| US-12162872-B2 | Cycloalkylurea derivative | Sumitomo Pharma Co., Ltd. (JP) | 2024-12-10 | — | — | US | disclosed |
| US-11814380-B2 | Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-11-14 | — | — | US | disclosed |
| WO-2023205778-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-26 | — | — | WO | disclosed |
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-22 | — | — | US | disclosed |
| US-20230088694-A1 | CYCLOALKYLUREA DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| EP-4067344-A1 | CYCLOALKYL UREA DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2022-10-05 | — | — | EP | disclosed |
| CN-115003655-A | Cycloalkyl urea derivatives | 住友制药株式会社 | 2022-09-02 | — | — | CN | disclosed |
| EP-2545045-B1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE HOLDINGS CORP (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2015152254-A1 | FIVE-MEMBERED RING HETEROARYL DERIVATIVE | 大日本住友製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |
| EP-2402325-B1 | Hydroxylated cyclopenta[d]pyrimidines as AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2015-08-26 | — | — | EP | disclosed |
| EP-2399909-B1 | Hydroxylated cyclopenta[d]pyrimidines as AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014153037-A1 | SUBSTITUTED TRIAZOLOPYRIDINES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014144545-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-2402325-A2 | Hydroxylated and methoxylated cyclopenta[d]pyrimidines as AKT protein kinase inhibitors | Array Biopharma, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| EP-2399909-A1 | Hydroxylated and methoxylated cyclopenta[d]pyrimidines as akt protein kinase inhibitors | Array Biopharma, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011112662-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION (US) | 2011-09-15 | — | — | WO | disclosed |
| WO-2008006040-A1 | HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-01-10 | — | — | WO | disclosed |