Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386865 | 1.00 | EPHX2 (0.39) | EPHX2TRPV1LMNAHDAC6FPR2 | |
| SCHEMBL27386866 | 1.00 | EPHX2 (0.39) | EPHX2TRPV1LMNAHDAC6FPR2 | |
| SCHEMBL30862728 | 0.90 | TRPV1 (0.40) | TRPV1LMNAHDAC6FPR2MAPT | |
| SCHEMBL30862836 | 0.86 | WRN (0.46) | EPHX2TRPV1LMNAFPR2MAPT | |
| SCHEMBL27386392 | 0.86 | WRN (0.46) | EPHX2TRPV1LMNAFPR2MAPT | |
| SCHEMBL30862689 | 0.84 | HDAC6 (0.43) | TRPV1LMNAHDAC6FPR2MAPT | |
| SCHEMBL27381226 | 0.80 | ENPP2 (0.41) | TRPV1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30862692 | 0.78 | WRN (0.44) | EPHX2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30862758 | 0.78 | WRN (0.44) | EPHX2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30862834 | 0.77 | TRPV1 (0.44) | TRPV1LMNAHDAC6FPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024079623-A1 | TRICYCLIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2024-04-18 | — | — | WO | disclosed |