Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | STK17B | O94768 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LATS1 | O95835 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867220 | 0.82 | LATS1 (0.45) | CYP3A4STK17BSTK17AMEN1KMT2A | |
| SCHEMBL7866101 | 0.81 | HPGD (0.46) | CYP3A4STK17BSTK17AMEN1KMT2A | |
| SCHEMBL2453025 | 0.81 | IDO1 (0.50) | CYP3A4STK17BSTK17AMEN1KMT2A | |
| SCHEMBL25122811 | 0.79 | CYP3A4 (0.54) | CYP3A4MEN1KMT2ATDP1LATS1 | |
| SCHEMBL27370470 | 0.79 | LMNA (0.44) | CYP3A4STK17BSTK17AMEN1KMT2A | |
| SCHEMBL25122892 | 0.78 | CYP3A4 (0.56) | CYP3A4MEN1KMT2ALMNATSHR | |
| SCHEMBL27507343 | 0.78 | CYP3A4 (0.71) | CYP3A4NPSR1 | |
| SCHEMBL16738634 | 0.76 | TDP1 (0.52) | STK17BSTK17AMEN1KMT2ATDP1 | |
| SCHEMBL7866002 | 0.76 | IDO1 (0.47) | CYP3A4STK17BSTK17AMEN1KMT2A | |
| SCHEMBL31568942 | 0.76 | IDO1 (0.46) | CYP3A4MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183142-C | Cephalosporin antibiotics, composition and application | ������ҩ��ҵ����˾ | 2005-01-05 | — | — | CN | disclosed |
| CN-1179963-C | Cephalosporin antibiotics, composition and application | ������ҩ��ҵ����˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1066735-C | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS INC (US) | 2001-06-06 | — | — | CN | disclosed |
| CN-1291612-A | Cephalosporin antibiotics | MAICROSEI MEDICINE CO (US) | 2001-04-18 | — | — | CN | disclosed |
| CN-1291611-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS INC (US) | 2001-04-18 | — | — | CN | disclosed |
| CN-1204336-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS INC (US) | 1999-01-06 | — | — | CN | disclosed |