SCHEMBL2738798

SCHEMBL2738798

NC(=O)N1c2ccccc2C=Cc2cc(O)ccc21

nearest known ligand 0.82

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 16/20 0.82
LMNA P02545 1/20 0.74
TSHR P16473 1/20 0.74
MAPK1 P28482 1/20 0.74
SCN4A P35499 1/20 0.74
SCN5A Q14524 1/20 0.74
SCN9A Q15858 1/20 0.74
P2RX1 P51575 5/20 0.45
P2RX3 P56373 5/20 0.45
P2RX7 Q99572 2/20 0.45
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
PTBP1 P26599 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamazepine SCHEMBL6477112 0.86 LMNA (1.00) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL29360181 0.86 LMNA (1.00) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL21639 0.86 LMNA (1.00) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL31685158 0.86 LMNA (1.00) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL29433237 0.86 LMNA (1.00) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL5382102 0.84 LMNA (0.96) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL1421962 0.84 LMNA (0.96) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL29023618 0.84 LMNA (0.96) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL29390487 0.84 LMNA (0.96) P2RX4LMNATSHRMAPK1SCN4A
Carbamazepine SCHEMBL27589204 0.84 LMNA (0.96) P2RX4LMNATSHRMAPK1SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118954850-A Method for removing organic pollutants by utilizing metal ion reinforced permanganate oxidation coagulation 四川大学 2024-11-15 CN disclosed
US-8569000-B2 Immunoassays using antibodies specific to carbamazepine Guangzhou Kingmed Center for Clinical Laboratory (CN) 2013-10-29 US disclosed
US-8569000-B2 Immunoassays using antibodies specific to carbamazepine Guangzhou Kingmed Center for Clinical Laboratory (CN) 2013-10-29 US disclosed
US-8563713-B2 Antibodies specific to carbamazepine Guangzhou Kingmed Center for Clinical Laboratory (CN) 2013-10-22 US disclosed
US-8563713-B2 Antibodies specific to carbamazepine Guangzhou Kingmed Center for Clinical Laboratory (CN) 2013-10-22 US disclosed
US-20120244557-A1 IMMUNOASSAYS USING ANTIBODIES SPECIFIC TO CARBAMAZEPINE Guangzhou Kingmed Center for Clinical Laboratory (CN) 2012-09-27 US disclosed
US-20120244557-A1 IMMUNOASSAYS USING ANTIBODIES SPECIFIC TO CARBAMAZEPINE Guangzhou Kingmed Center for Clinical Laboratory (CN) 2012-09-27 US disclosed
US-20120244546-A1 ANTIBODIES SPECIFIC TO CARBAMAZEPINE Guangzhou Kingmed Center for Clinical Laboratory (CN) 2012-09-27 US disclosed
US-20120244546-A1 ANTIBODIES SPECIFIC TO CARBAMAZEPINE Guangzhou Kingmed Center for Clinical Laboratory (CN) 2012-09-27 US disclosed
US-8088918-B2 Noncardiotoxic pharmaceutical compounds WILLIAMSBURG HOLDINGS LLC (US) 2012-01-03 US disclosed
US-8088918-B2 Noncardiotoxic pharmaceutical compounds WILLIAMSBURG HOLDINGS LLC (US) 2012-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120244546-A1 ANTIBODIES SPECIFIC TO CARBAMAZEPINE CACNA2D3, CACNA2D4, CACNA2D2 P2RX4 2361/4885LMNA 4287/4885TSHR 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.