Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 15/20 | 0.41 |
| ▸ | WEE1 | P30291 | 4/20 | 0.37 |
| ▸ | MYT1 | Q01538 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.35 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | EPHB1 | P54762 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388129 | 0.81 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL27397921 | 0.77 | PKMYT1 (0.44) | PKMYT1 | |
| SCHEMBL27388136 | 0.76 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971257 | 0.76 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL27398742 | 0.74 | PKMYT1 (0.46) | PKMYT1WEE1MYT1EPHB3 | |
| SCHEMBL27388126 | 0.72 | PKMYT1 (0.44) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27388124 | 0.71 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971250 | 0.71 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL31344839 | 0.71 | PKMYT1 (0.39) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971272 | 0.69 | SYK (0.44) | PKMYT1WEE1MYT1CDK1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |