Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 7/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | WEE1 | P30291 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | FGR | P09769 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388124 | 1.00 | PKMYT1 (0.41) | PKMYT1ARCYP2C9KDM4EBRD4 | |
| SCHEMBL30971229 | 0.85 | AR (0.38) | PKMYT1ARALDH1A1SMN1; SMN2 | |
| SCHEMBL30971257 | 0.81 | PKMYT1 (0.41) | PKMYT1ARCREBBPWEE1CDK1 | |
| SCHEMBL27388136 | 0.81 | PKMYT1 (0.41) | PKMYT1ARCREBBPWEE1CDK1 | |
| SCHEMBL27387958 | 0.79 | PKMYT1 (0.41) | PKMYT1CYP2C9CREBBPWEE1CDK1 | |
| SCHEMBL30971207 | 0.79 | PKMYT1 (0.41) | PKMYT1CYP2C9CREBBPWEE1CDK1 | |
| SCHEMBL20674053 | 0.78 | BRD4 (0.41) | ARKDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL21440749 | 0.78 | KDM4E (0.41) | ARKDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL27388129 | 0.76 | PKMYT1 (0.41) | PKMYT1CYP2C9BRD4ALDH1A1CREBBP | |
| SCHEMBL30971295 | 0.76 | LMNA (0.38) | ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |